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Mesothelioma Awareness Day

Honoring Mesothelioma Awareness Day 2014 by Supporting Medical Research

mesothelioma awareness day 2014Mesothelioma Awareness Day 2014 is September 26. But here at Kazan Law, in a way every day is Mesothelioma Awareness Day. Because our work in asbestos litigation brings us close to those whose lives are forever impacted by mesothelioma, we seek not only justice for mesothelioma victims and their families, but also advances in mesothelioma medical research. Through our firm and our firm’s foundation, we help support mesothelioma research at leading medical facilities all over the world. But we place special emphasis on two here in the Bay Area: the University of California San Francisco (UCSF) and Stanford University. Not only are they top notch, they also have helped care for many of our clients.

Like pieces of a jigsaw puzzle, scientific medical research involves finding many small intricate pieces that in the end will fit together to solve the puzzle. We are proud to support scientists in trying to fit together all those parts on a microbiological level to advance knowledge about mesothelioma.

Here are ten recently published research papers where our foundation’s support is noted in the acknowledgements section:

1.The expression of Dishevelled-3 and glutamine metabolism in malignant pleural mesothelioma

Researchers: Tong Li, Sheng-Cai Hou, Jian-Hua Mao, et al.

Research Institution: The University of California San Francisco

Publication: Journal of Clinical Pathology   Citation: J Clin Pathol 2012 65: 855-858

2.Cul4A is an oncogene in malignant pleural mesothelioma

Researchers: Ming-Szu Hung, Jian-Hua Mao, Zhidong Xu, Cheng-Ta Yang, Jau-Song Yu, Chansonette Harvard, Yu-Ching Lin, Dawn Therese Bravo, David M. Jablons, Liang You


Research Institution: University of California San Francisco

Publication: Journal of Cell Molecular Medicine   Citation: J. Cell. Mol. Med. Vol 15, No 2, 2011 pp. 350-358

3.Gli as a Novel Therapeutic Target in Malignant Pleural Mesothelioma

Researchers: Hui Li , Natalie Lui , Tiffany Cheng , Hsin-Hui K. Tseng , Dongsheng Yue, Etienne Giroux-Leprieur, \\

Research Institution: The University of California San Francisco

Publication: The Public Library of Science (PLOS) Citation: PLOS ONE | www.plosone.org 1 March 2013 | Volume 8 | Issue 3 | e57346

4.The homeobox gene EMX2 is a prognostic and predictive marker in malignant pleural mesothelioma

Researchers: Etienne Giroux Leprieur, Tomomi Hirata, Minli Mo, Zhao Chen, Junichi Okamoto, Genevieve Clement, Hui Li, Marie Wislez, David M. Jablons, Biao He

Research Institution: The University of California San Francisco

Publication: Lung Cancer Journal   Citation: Lung Cancer (2014), http://dx.doi.org/10.1016/j.lungcan.2014.06.018

5.Inhibition of activated phosphatidylinositol 3-kinase/AKT pathway in malignant pleural mesothelioma leads to G1 cell cycle arrest

Researchers: Iwao Mikami, Fang Zhang1, Tomomi Hirata, Junichi Okamoto, Kiyoshi Koizumi, Kazuo Shimizu, David Jablons and Biao He

Research Institution: The University of California San Francisco

Publication: Oncology Reports   Citation: Oncology Reports 24: 1677-1681, 2010

6.SMO expression level correlates with overall survival in patients with malignant pleural mesothelioma

Researchers: Yi Zhang, Jianxing He, Fang Zhang, Hui Li, Dongsheng Yue, Changli Wang, David M Jablons, Biao He and Natalie Lui

Research Institution: The University of California San Francisco

Publication: Journal of Experimental & Clinical Cancer Research Citation: Journal of Experimental & Clinical Cancer Research 2013, 32:7 http://www.jeccr.com/content/32/1/7

7.The expression of CXCR4, CXCL12 and CXCR7 in malignant pleural mesothelioma

Researchers: Tong Li, Hui Li, Yucheng Wang,Chansonette Harvard, Jia-Li Tan, Alfred Au,7 Zhidong Xu, David M Jablons and Liang You

Research Institution: The University of California San Francisco

Publication: Journal of Pathology  Citation: J Pathol 2011; 223: 519–530

8.Targeting Gli transcription activation by small molecule suppresses tumor growth

Researchers: G. Bosco-Clement, F. Zhang, Z .Chen, H-M Zhou, H. Li, I. Mikami, Hirata, A. Yagui-Beltran, N Lu, H.T. Do

Research Institution: The University of California San Francisco

Publication: Oncogene   Citation: Oncogene (2014) 33, 2087–2097

9.Transgenic Mice for Cre-Inducible Overexpression of the Cul4A Gene

Researchers: Tong Li,Ming-Szu Hung,Yucheng Wang,Jian-Hua Mao, Jia-Li Tan,Kenneth Jahan, Hannah Roos,Zhidong Xu, David M. Jablons and Liang You

Research Institution: The University of California San Francisco

Publication: Genesis: The Journal of Genetics and Development     Citation: genesis 49:134–141 (2011)

10.miR-1 Induces Growth Arrest and Apoptosis in Malignant Mesothelioma

Researchers: Yue Xu , PhD ; Ming Zheng , PhD ; Robert E. Merritt , MD ; Joseph B. Shrager , MD ; Heather A. Wakelee , MD ; Robert A. Kratzke , MD ; and Chuong D. Hoang , MD

Research Institution: Stanford University

Publication: Chest   Citation: Chest 2013; 144(5):1632–1643

Mesothelioma Awareness Day Events Generate Nationwide Attention

Meso_Awareness_DayMesothelioma patients and their families confront the malignant asbestos-caused cancer every day but yesterday all across the US many people got their first introduction to the often fatal illness, including those in a position to do something about it.  These included everyone from Congressional representatives in Washington DC to college students in Florida and Arizona who participated in fundraising runs to support mesothelioma patients.

Started by the Mesothelioma Applied Research Foundation (MARF) in 2004, Meso Awareness Day event organizers have steadily scaled up their efforts to familiarize the general public about this deadly type of cancer caused by asbestos exposure primarily in the workplace or asbestos-containing products in the home.  About 3,000 Americans are diagnosed with mesothelioma each year.

MARF is the only national non-profit organization entirely dedicated to ending mesothelioma by funding research, providing education and support for patients and their families, and by advocating for federal funding of mesothelioma research.

With dozens of events occurring around the nation and more scheduled for this weekend, here are a few highlights of Meso Awareness Day 2013 thus far:

  • MARF members held a Congressional Briefing at 10 a.m. yesterday in the Rayburn Office Building. Their presentation was called “Mesothelioma: Unknown, Underfunded and Incurable.”
  • A large group of MARF supporters gathered at New York City’s Rockefeller Center for the taping of the Today Show were visible in their bright yellow shirts. Today Show Al Roker briefly spoke with the group .
  • The Baltimore Orioles, during their game against the Toronto Blue Jays, recognized Meso Awareness Day by featuring information about the Meso Foundation on the jumbotron screen.

Kazan Law is proud to be listed on the Annual Donors page on MARF’s website.  We are pleased to know that through donations from the Kazan, McClain, Abrams, Fernandez, Lyons, Greenwood, Oberman, Satterly & Bosl Foundation, Inc., we are part of who MARF is talking about when they state:

“Because of your support, the Foundation funds the highest-quality, peer-reviewed research, provides education and support to patients and their loved ones and leads advocacy efforts to increase federal funding for research and increase awareness of mesothelioma.”

We believe that thanks to MARF’s efforts like Meso Awareness Day, mesothelioma will not be unknown, underfunded and maybe not even incurable in the future.

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